Locus Coeruleus Activity Strengthens Prioritized Memories Under Arousal
نویسندگان
چکیده
منابع مشابه
COERULEUS MOTIVATED MEMORY 1 1 2 3 4 5 Locus coeruleus activity strengthens prioritized 6 memories under arousal
34 Recent models posit that bursts of locus coeruleus (LC) activity amplify neural gain, such that 35 limited attention and encoding resources focus even more on prioritized mental representations 36 under arousal. Here, we tested this hypothesis in human males and females using functional 37 magnetic resonance imaging (fMRI), neuromelanin MRI, and pupil dilation, a biomarker of 38 arousal and ...
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Mood, motivation, attention, and arousal are behavioral states having a profound impact on cognition. Behavioral states are mediated though the peripheral nervous system and neuromodulatory systems in the brainstem. The noradrenergic nucleus locus coeruleus is activated in parallel with the autonomic system in response to biological imperatives. These responses can be spontaneous, to unexpected...
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The locus coeruleus-noradrenergic (LC-NA) neuromodulatory system has been implicated in a broad array of cognitive processes, yet scope for investigating this system's function in humans is currently limited by an absence of reliable non-invasive measures of LC activity. Although pupil diameter has been employed as a proxy measure of LC activity in numerous studies, empirical evidence for a rel...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 2018
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.2097-17.2017